Norrin, Human

• UNSPSC Description:

  Norrin protein activates canonical Wnt signaling by binding to FZD4 and LRP5, promotes retinal vascularization and stabilizes β-catenin (CTNNB1). It cooperates with TSPAN12 to independently activate FZD4, suggesting a Wnt-independent mechanism. Norrin Protein, Human is the recombinant human-derived Norrin protein, expressed by E. coli , with tag free. The total length of Norrin Protein, Human is 109 a.a., with molecular weight of ~13 kDa.

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/norrin-protein-human.html

• Purity:

  96.0

• Smiles:

  KTDSSFIMDS DPRRCMRHHY VDSISHPLYK CSSKMVLLAR CEGHCSQASR SEPLVSFSTV LKQPFRSSCH CCRPQTSKLK ALRLRCSGGM RLTATYRYIL SCHCEECNS

• Molecular Weight:

  Approximately 13 kDa

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stored at -20°C for 2 years