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POU5F1 Antibody / OCT4

CAT: 0013-GTR18294015-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18294015-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OCT4/POU5F1 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. It is a key regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4/POU5F1 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testis.
UniProt
Q01860
Reactivity
Human
Immunogen
Recombinant fragment from the human protein was used as the immunogen for the POU5F1 antibody.
Clonality
Recombinant
Clone
OCT4/6847R
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the POU5F1 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG, kappa

UniProtKB · Q01860

POU domain, class 5, transcription factor 1

PO5F1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q01860
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POU5F1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NCS1, A6NLL8, D2IYK4, P31359, Q15167, Q15168, Q16422, Q5STF3, Q5STF4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

Developmental proteinDNA-binding

Domain

Homeobox

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Biological process

TranscriptionTranscription regulation

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