Galnon (TFA)

CAT: 0804-HY-103536A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-103536A-01Size:5 mg
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Description
Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects[1][2].
CAS Number
[1217448-19-5]
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/galnon-tfa.html
Purity
98.88
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(C(F)(F)F)=O.CC(C1=CC=C(C=C1O2)NC([C@H](CCCCN)NC([C@H](CC3CCCCC3)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O)=O)=O)=CC2=O
Molecular Formula
C42H47F3N4O8
Molecular Weight
792.84
References & Citations
[1]Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101 (28) :10470-5.|[2]Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41 (5) :307-20.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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