Anti-GLUT10 Antibody

Anti-GLUT10 Antibody

• Description: Rabbit Polyclonal Antibody specific to GLUT10
• Alternative Name: Glucose transporter type 10, GLUT-10
• Gene Name: SLC2A10
• NCBI Gene ID: SLC2A10
• UniProt: O95528
• Cellular Locus: Endomembrane system, Cytoplasm, perinuclear region
• Host: Rabbit
• Reactivity: Human
• Immunogen: Synthetic peptide corresponding to amino acids 367-385 (ILSTAKKTKPHPRSGDPSA) of human GLUT10 conjugated to KLH at the N- terminus.
• Target Antigen: Solute carrier family 2, facilitated glucose transporter member 10
• Target: GLUT10
• Clonality: Polyclonal
• Type: Antibody
• Applications: WB
• Field of Research: Neuroscience
• Purification Method: Purified by peptide immuno-affinity chromatography
• Concentration: Lot Specific
• Dilution: Dilute in PBS or medium that is identical to that used in the assay system.
• Format: Purified
• Form: Liquid
• Buffer: Phosphate Buffered Saline
• Function: Facilitative glucose transporter required for the development of the cardiovascular system. {PubMed:11592815, PubMed:16550171}.
• Additionnal Information: Immunoblotting: use at 1:500 dilution. A band of approximately 57 kDa is detected.
  
  Positive control: transfected cell lysate
• Storage Conditions: This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
• Specificity: This antibody recognizes human GLUT10.
• Formulation: PBS, pH 7.4.
• Buffer pH: pH 7.4
• Target Background: Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetic causes. Genome-wide screening has identified several susceptibility loci for NIDDM within the human genome. Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (GLUT or SLC2A family). The gene for GLUT10, localized to human chromosome 20q12-q13.1, is a candidate gene for NIDDM susceptibility. It is widely expressed, with highest levels in liver and pancreas.