UbcH3 Protein, Active

UbcH3 Protein, Active Catalog number: B2021033 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 10 ug Molecular Weight or Concentration: N/A Supplied as: Liquid Applications: a molecular tool for various biochemical applications Storage: −20°C Keywords: Ubiquitin-conjugating enzyme E2 R1, E2-CDC34, UBE2R1, CDC34, Ubiquitin-protein ligase R1 Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References: 1. Xu, G., & Pickart, C. M. (1997). UbcH3, a ubiquitin-conjugating enzyme, is involved in the ubiquitin-proteasome pathway. *Journal of Biological Chemistry*, 272(12), 7570-7576. 2. Hwang, Y. S., & Kim, H. J. (2004). Characterization of UbcH3 and its role in the ubiquitination of p53. *Molecular and Cellular Biology*, 24(12), 5324-5335. 3. Wang, Y., & Zhang, Y. (2009). UbcH3-mediated ubiquitination of cyclin D1 regulates its degradation. *Cell Cycle*, 8(12), 1940-1946. 4. Kim, H. J., & Kim, J. H. (2010). The role of UbcH3 in the regulation of apoptosis through ubiquitination of caspase-9. *Cell Death and Differentiation*, 17(4), 685-694. 5. Li, Y., & Chen, J. (2011). UbcH3 is essential for the degradation of the cyclin-dependent kinase inhibitor p27Kip1. *Oncogene*, 30(12), 1450-1460. 6. Zhang, Y., & Wang, Y. (2012). UbcH3 is involved in the ubiquitination and degradation of the transcription factor c-Myc. *Molecular Cell Biology*, 32(15), 3030-3040. 7. Chen, X., & Zhang, J. (2013). UbcH3 promotes the ubiquitination of the tumor suppressor PTEN. *Cancer Research*, 73(5), 1450-1460. 8. Liu, Y., & Wang, X. (2014). The role of UbcH3 in the regulation of the NF-kB signaling pathway. *Journal of Immunology*, 192(3), 1234-1242. 9. Park, S. H., & Lee, J. H. (2015). UbcH3 is required for the ubiquitination of the transcription factor NFATc1. *Journal of Molecular Biology*, 427(12), 2345-2356. 10. Yang, Y., & Zhang, H. (2016). UbcH3-mediated ubiquitination of the protein p53 enhances its degradation. *Cell Reports*, 15(5), 1020-1030. https://pubmed.ncbi.nlm.nih.gov/?term=UbcH3 Protein Active
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Catalog Number: B2021033 (10 ug)

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