UbcH7 Protein, Active

UbcH7 Protein, Active_x000D_ Catalog number: B2018566_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5 µg_x000D_ Molecular Weight or Concentration: N/A_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: Ubiquitin-conjugating enzyme E2 L3, L-UBC, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2-F1, Ubiquitin-protein ligase L3, UBE2L3, UBCE7_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Niu K, Fang H, Chen Z, Zhu Y, Tan Q, Wei D, Li Y, Balajee AS, Zhao Y. USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy Autophagy. 2020 Apr;16(4):724-734._x000D_ 2: Verma S, Ismail A, Gao X, Fu G, Li X, O'Malley BW, Nawaz Z. The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors Mol Cell Biol. 2004 Oct;24(19):8716-26._x000D_ 3: Whitcomb EA, Tsai YC, Basappa J, Liu K, Le Feuvre AK, Weissman AM, Taylor A. Stabilization of p27(Kip1)/CDKN1B by UBCH7/UBE2L3 catalyzed ubiquitinylation: a new paradigm in cell-cycle control FASEB J. 2019 Jan;33(1):1235-1247._x000D_ 4: Wenzel DM, Lissounov A, Brzovic PS, Klevit RE. UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids Nature. 2011 Jun 2;474(7349):105-8._x000D_ 5: Singh A, Tiwari S, Singh S. Pirh2 modulates amyloid-β aggregation through the regulation of glucose-regulated protein 78 and chaperone-mediated signaling J Cell Physiol. 2023 Dec;238(12):2841-2854._x000D_ 6: Zheng N, Wang P, Jeffrey PD, Pavletich NP. Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases Cell. 2000 Aug 18;102(4):533-9._x000D_ 7: Moynihan TP, Ardley HC, Nuber U, Rose SA, Jones PF, Markham AF, Scheffner M, Robinson PA. The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1 J Biol Chem. 1999 Oct 22;274(43):30963-8._x000D_ 8: Zhang X, Huo C, Liu Y, Su R, Zhao Y, Li Y. Mechanism and Disease Association With a Ubiquitin Conjugating E2 Enzyme: UBE2L3 Front Immunol. 2022 Feb 21;13:793610._x000D_ 9: Condos TE, Dunkerley KM, Freeman EA, Barber KR, Aguirre JD, Chaugule VK, Xiao Y, Konermann L, Walden H, Shaw GS. Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation EMBO J. 2018 Dec 3;37(23):e100014._x000D_ 10: Simmons A, Gangadharan B, Hodges A, Sharrocks K, Prabhakar S, García A, Dwek R, Zitzmann N, McMichael A. Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T cells to positively regulate signaling Immunity. 2005 Dec;23(6):621-34. _x000D_ _x000D_ Products Related to UbcH7 Protein, Active can be found at Proteins

Catalog Number: B2018566 (5 µg)

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