TDRL-551

CAT: 0804-HY-114842-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-114842-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TDRL-551 is a potent replication protein A (RPA) inhibitor (IC50 = 18 µM) . TDRL-551 inhibits RPA-DNA interaction and increases the anti-cancer efficacy of Platinum (Pt) -based chemotherapy. TDRL-551 can be used for the research of cancer, such as non-small cell lung cancer (NSCLC) [1].
CAS Number
[1644626-43-6]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tdrl-551.html
Purity
99.84
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(CCCC(N1N=C(CC1C2=CC3=CC=C(C=C3N=C2Cl)OCC)C4=CC=C(C=C4)I)=O)O
Molecular Formula
C25H23ClIN3O4
Molecular Weight
591.83
References & Citations
[1]Mishra AK, et al. Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancer. Biochem Pharmacol. 2015 Jan 1;93 (1) :25-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-139038-01TDRL-X80
HY-19779-01JTT 551
HY-W556870-01OT-551
HY-W953793CRBN ligand-551
HY-106429OT-551 (free base)
HY-160160-01BAY-5516
HY-119707TDR 32750
HY-R01711A-01Hsa-miR-551a agomir
HY-R01711-01Hsa-miR-551a mimic
HY-RS14341TDRP Human Pre-designed siRNA Set A

Alternative Products

CatalogName
BUP06306-01TDRL-551
MBS5805410TDRL-X80
MBS5777965OT-551
MF-0022678-01JTT 551
MBS3605929-01JTT-551
ABC-TC0207Detroit 551
534791MS 551
MBS5802400OT-551 HCl
A20776-100JTT 551 100mg
BML-AR104-0010ICI-118,551

Popular Products