JTT 551
CAT:
804-HY-19779-03
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

JTT 551
- CAS Number: 776309-04-7
- UNSPSC Description: JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively; JTT 551 can be used in the research of type 2 diabetes mellitus.
- Target Antigen: Phosphatase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/JTT_551.html
- Purity: 99.65
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(O)CN(CC1=NC=C(C(C)(C)C)S1)CC2=NC(C3=CC=C(COC4=CC=C(C(CCC)CCC)C=C4)C=C3)=CS2
- Molecular Weight: 605.85
- References & Citations: [1]Fukuda S, et al. Pharmacological profiles of a novel protein tyrosine phosphatase 1B inhibitor, JTT-551. Diabetes Obes Metab. 2010 Apr;12(4):299-306.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported