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AMG580

CAT: 0804-HY-124392Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124392Size:1 Each
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Description
AMG580 is a selective PDE10A antagonist with subnanomolar affinity for rat, primate, and human PDE10A. AMG580 can be used for the research of noninvasive radiotracer[1].
CAS Number
1227067-71-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amg580.html
Smiles
O=C(C1=NC2=C(N1)C=CC=C2)C3=CC=C(C=C3)OC4=NC=CN=C4C5CCN(CC5)C(C(C)F)=O
Molecular Formula
C26H24FN5O3
Molecular Weight
473.50
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Chen H, et al. AMG 580: a novel small molecule phosphodiesterase 10A (PDE10A) positron emission tomography tracer. J Pharmacol Exp Ther. 2015 Feb;352 (2) :327-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE10

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CatalogName
T201731-01AMG580

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