SWELYYPLRANL-NH2 (TFA)

SWELYYPLRANL-NH2 (TFA)

• UNSPSC Description: SWELYYPLRANL-NH2 TFA is an E-cadherin and N-cadherin antagonist. SWELYYPLRANL-NH2 TFA inhibits phage clone binding to E- or N-cad/Fc chimeric protein (IC50: 0.7 and 0.09 μM respectively). SWELYYPLRANL-NH2 TFA inhibits cell aggregation. SWELYYPLRANL-NH2 can be used to promote drug delivery through epithelial and endothelial permeability barriers[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/swelyyplranl-nh2-tfa.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC4=CC=C(C=C4)O)C(N5[C@@H](CCC5)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N.O=C(C(F)(F)F)O.[x]
• Molecular Weight: 1523.73 (free acid)
• References & Citations: [1]Devemy E, et al. Identification of a novel dual E- and N-cadherin antagonist. Peptides. 2009 Aug;30(8):1539-47.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported