Mal-NH2 (TFA)

• Description :

  Mal-NH2 (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mal-nh2-tfa.html

• Purity :

  99.32

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C=C1)N(CCN)C1=O.O=C(O)C(F)(F)F

• Molecular Formula :

  C8H9F3N2O4

• Molecular Weight :

  254.16

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Alkyl-Chain Linkers

• CAS Number :

  [146474-00-2]