(Z)-Pitavastatin (calcium)

(Z)-Pitavastatin (calcium)

• CAS Number: 1159588-21-2
• UNSPSC Description: (Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/z-pitavastatin-cacium.html
• Smiles: FC(C=C1)=CC=C1C2=C(/C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)C(C3CC3)=NC4=C2C=CC=C4.[1/2].[Ca+2]
• Molecular Weight: 440.49
• References & Citations: [1]Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.
• Shipping Conditions: Room temperature