(Z)-Pitavastatin (calcium)

• UNSPSC Description:

  (Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/z-pitavastatin-cacium.html

• Smiles:

  FC(C=C1)=CC=C1C2=C(/C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)C(C3CC3)=NC4=C2C=CC=C4.[1/2].[Ca+2]

• Molecular Weight:

  440.49

• References & Citations:

  [1]Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.

• Shipping Conditions:

  Room temperature

• CAS Number:

  1159588-21-2