PTBP1-RNA-binding inhibitor P6 (TFA)

CAT:

804-HY-P5960-03

Size:

10 mg

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UNSPSC Description: PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide inhibitor of the splicing factor PTBP1, which inhibits alternative splicing events regulated by PTBP1. PTBP1 binds RNA through its RNA recognition motif[1].
Target Antigen: Others
Type: Peptides
Related Pathways: Others
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/ptbp1-rna-binding-inhibitor-p6-tfa.html
Purity: 98.43
Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL
Smiles: O=C(N[C@@H](CCC(N)=O)C(N[C@@](C)(CCC/C=C\CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@]21C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@](CCC/C=C\CCC2)(C)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(N)=O)NC(C)=O.xO=C(O)C(F)(F)F
Molecular Weight: 1597.86 (free base)
References & Citations: [1]Schmeing S, et al. Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding. Chem Sci. 2023 Jul 13;14(31):8269-8278.
Shipping Conditions: Blue Ice
Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Clinical Information: No Development Reported

Cat	Name
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