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Endotoxin inhibitor (TFA)

CAT: 0804-HY-P3912A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P3912A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Endotoxin inhibitor TFA is a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor TFA inhibits the febrile response to LPS with very low toxicity and lethality[1].
UNSPSC
12352209
Target
Interleukin Related
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/endotoxin-inhibitor-tfa.html
Purity
99.77
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)C(O)=O)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@@H](N)CCCCN)=O)=O)=O)=O)CCCCN)N[C@H]1CC2=CC=CC=C2.OC(C(F)(F)F)=O.[6]
Molecular Formula
C67H103F18N15O24S2
Molecular Weight
1908.72
References & Citations
[1]Toshihiko Katafuchi, et al. Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Res Mol Brain Res. 2003 Oct 21;118 (1-2) :24-32.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

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