Endotoxin inhibitor (TFA)

Endotoxin inhibitor (TFA)

• UNSPSC Description: Endotoxin inhibitor TFA is a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor TFA inhibits the febrile response to LPS with very low toxicity and lethality[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/endotoxin-inhibitor-tfa.html
• Purity: 99.77
• Solubility: H2O : 100 mg/mL (ultrasonic)
• Smiles: O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)C(O)=O)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@@H](N)CCCCN)=O)=O)=O)=O)CCCCN)N[C@H]1CC2=CC=CC=C2.OC(C(F)(F)F)=O.[6]
• Molecular Weight: 1908.72
• References & Citations: [1]Toshihiko Katafuchi, et al. Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Res Mol Brain Res. 2003 Oct 21;118(1-2):24-32.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported