Rac1 Inhibitor W56 (TFA)

Rac1 Inhibitor W56 (TFA)

• UNSPSC Description: Rac1 Inhibitor W56 TFA is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor W56 TFA inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam[1].
• Target Antigen: Ras
• Type: Peptides
• Related Pathways: GPCR/G Protein;MAPK/ERK Pathway
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/rac1-inhibitor-w56-tfa.html
• Purity: 99.98
• Solubility: H2O : 100 mg/mL (ultrasonic)
• Smiles: OC(CNC([C@H](C)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(C)C)NC(CNC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H]1N(CCC1)C([C@H](CCCCN)NC(CNC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@@H](N)CCSC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
• Molecular Weight: 1671.93 (free acid)
• References & Citations: [1]Gao Y, Xing J, et al. Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors [published correction appears in J Biol Chem. 2005 Jan 14;280(2):1704]. J Biol Chem. 2001;276(50):47530-47541.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported