Mc-VC-PAB-SN38
CAT:
804-HY-131057-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mc-VC-PAB-SN38
- CAS Number: 1801838-28-7
- UNSPSC Description: Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
- Target Antigen: Drug-Linker Conjugates for ADC
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/mc-vc-pab-sn38.html
- Purity: 96.38
- Solubility: DMSO : 28.57 mg/mL (ultrasonic)
- Smiles: O=C1OCC(C2=O)=C(C=C(N2CC3=C(CC)C4=C5)C3=NC4=CC=C5O)[C@]1(CC)OC(OCC6=CC=C(C=C6)NC([C@@H](NC([C@@H](NC(CCCCCN7C(C=CC7=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)=O
- Molecular Weight: 991.05
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported