Lycoramine (hydrobromide)

• UNSPSC Description:

  Lycoramine hydrobromide, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine hydrobromide is a potent acetylcholinesterase (AChE) inhibitor[1][2].

• Target Antigen:

  Cholinesterase (ChE)

• Type:

  Natural Products

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/lycoramine-hydrobromide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1CC[C@@]23CCN(C)CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24.[H]Br

• Molecular Weight:

  370.28

• References & Citations:

  [1]Yuan Y, et, al. Online acetylcholinesterase inhibition evaluation by high-performance liquid chromatography-mass spectrometry hyphenated with an immobilized enzyme reactor. J Chromatogr A. 2020 Jan 4; 1609:460506.|[2]IRWIN RL, et, al. Cholinesterase inhibition by galanthamine and lycoramine. Biochem Pharmacol. 1960 May; 3:147-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  89505-76-0