PARP-1-IN-23

PARP-1-IN-23

• CAS Number: 2976497-48-8
• UNSPSC Description: PARP-1-IN-23 (Compound I16 ) is an orally active and selective PARP-1 inhibitor with the IC50 of 12.38 nM. PARP-1-IN-23 inhibits tumor growth in vivo[1].
• Target Antigen: PARP
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/parp-1-in-23.html
• Smiles: BrC1=CC(C2=NC3=C(C=CC=C3N2)C(N)=O)=CC(OC)=C1OS(=O)(C4=CC=CC=C4C)=O
• Molecular Weight: 516.36
• References & Citations: [1]Zhang Y, et al. Design of Selective PARP-1 Inhibitors and Antitumor Studies. J Med Chem. 2024;67(11):8877-8901.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported