Hydroxypropyl Cellulose

CAT: 0804-HY-100557-01Size: 10 gDry Ice: NoHazardous: No
CAT#:0804-HY-100557-01Size:10 g
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hydroxypropyl Cellulose is an orally active cellulose ether and surfactant. Hydroxypropyl cellulose is divided into high-substituted HPC (HHPC) and low-substituted HPC (LHPC) . Hydroxypropyl Cellulose reduces inflammatory mediators (IL-6, IL-1β) . Hydroxypropyl Cellulose improves colitis and obesity. Hydroxypropyl Cellulose can be used as a pharmaceutical excipient, such as coating agent, emulsifier, suspension, tablet, thickener, viscosifier[1][2][3][4].
CAS Number
[9004-64-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hydroxypropyl-cellulose.html
Purity
97.0
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
CO[C@H]1C(O[R])[C@@H](O[R])[C@H](C)O[C@@H]1CO[R].[n].[R=HorCH2CH(OH)CH3]
Precautions
H302, H315, H319, H335
References & Citations
[1]Werbowyj R S, et al. Liquid crystalline structure in aqueous hydroxypropyl cellulose solutions[J]. Molecular Crystals and Liquid Crystals, 1976, 34 (4) : 97-103.|[2]Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.|[3]Li X, et al. The potential therapeutic effects of hydroxypropyl cellulose on acute murine colitis induced by DSS. Carbohydr Polym. 2022 Aug 1;289:119430.|[4]Kim H, et al. Altered hepatic gene expression profiles associated with improved fatty liver, insulin resistance, and intestinal permeability after hydroxypropyl methylcellulose (HPMC) supplementation in diet-induced obese mice. J Agric Food Chem. 2013 Jul 3;61 (26) :6404-11.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
Launched

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