Hydroxypropyl-beta-cyclodextrin

Hydroxypropyl-beta-cyclodextrin

• CAS Number: 107745-73-3
• UNSPSC Description: Hydroxypropyl-beta-cyclodextrin is a SARS-CoV-2 inhibitor. Hydroxypropyl-beta-cyclodextrin has immunomodulatory effects, which can reduce the production of inflammatory cytokines in lung epithelial cells infected by the virus[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/hydroxypropyl-beta-cyclodextrin.html
• Smiles: CC(O)COC[C@@H](O[C@@](O[C@]([C@@H]1O)([H])[C@H](O[C@@](O[C@]([C@@H]2O)([H])[C@H](O[C@@](O[C@]([C@@H](C3O)O)([H])[C@H]4COCC(O)C)([H])[C@@H]2O)COCC(O)C)([H])[C@@H]1O)COCC(O)C)([H])[C@@H]5O)[C@@]([C@@H]5O)([H])O[C@@]([C@@H]([C@H]6O)O)([H])O[C@@H]([C@@]6([H])O[C@@]([C@@H]([C@H]7O)O)([H])O[C@@H]([C@@]7([H])O[C@@]([C@@H]([C@H]8O)O)([H])O[C@@H]([C@@]8([H])O[C@@]3([H])O4)COCC(O)C)COCC(O)C)COCC(O)C
• Molecular Weight: 1541.54
• References & Citations: [1]Bezerra BB, et al. Hydroxypropyl-beta-cyclodextrin (HP-BCD) inhibits SARS-CoV-2 replication and virus-induced inflammatory cytokines. Antiviral Res. 2022 Sep;205:105373.
• Shipping Conditions: Room temperature
• Clinical Information: Phase 3