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Junceellolide C

CAT: 0804-HY-N10404Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10404Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Junceellolide C is a transcription inhibitor of cccDNA. Junceellolide C inhibits HBV DNA replication and significantly decreases the level of supernatant HBV RNA with EC50 values of 5.19, 3.52 μM respectively in HepAD38 cells. Junceellolide C is a potent anti-HBV agent[1].
CAS Number
121769-82-2
UNSPSC
12352005
Target
HBV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/junceellolide-c.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]([C@@H]([C@]3([C@@]([C@H](C(/C=C\[C@@H]2OC(C)=O)=C)Cl)([H])OC([C@@H]3C)=O)O)OC(C)=O)([H])[C@]4(CC[C@@H]1OC(C)=O)CO4
Molecular Formula
C26H33ClO10
Molecular Weight
540.99
References & Citations
[1]Jiru Wu, et al. Briarane-type diterpenoids from a gorgonian coral Ellisella sp. with anti-HBV activities. Bioorg Chem. 2020 Dec;105:104423.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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