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PD-1/PD-L1-IN-NP19

CAT:
804-HY-131347-04
Size:
25 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
PD-1/PD-L1-IN-NP19 - image 1

PD-1/PD-L1-IN-NP19

  • CAS Number: 2377916-66-8
  • UNSPSC Description: PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12.5 nM for human PD-1/PD-L1 interaction. PD-1/PD-L1-IN-NP19 could activate the immune microenvironment in tumor, which may contribute to its antitumor effects[1].
  • Target Antigen: PD-1/PD-L1
  • Type: Reference compound
  • Related Pathways: Immunology/Inflammation
  • Field of Research: Cancer; Inflammation/Immunology
  • Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-np19.html
  • Purity: 98.25
  • Solubility: DMSO : 2 mg/mL (ultrasonic)
  • Smiles: CC(C)(NCC1=CC(Cl)=C(OCC2=C(C)C(C3=CC=CC=C3)=CC=C2)C=C1OCC4=CC=CC(C#N)=C4)C(O)=O
  • Molecular Weight: 555.06
  • References & Citations: [1]Cheng B, et, al. Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction As Potential Anticancer Agents. J Med Chem. 2020 Jul 15.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
  • Clinical Information: No Development Reported

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