Mps-BAY2a

• Description :

  Mps-BAY2a is a monopolar spindle 1 (MPS1) inhibitor with an IC50 of 1 nM against human MPS1. Mps-BAY2a induces mitotic aberrations and apoptosis in cancer cells[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Mps1

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mps-bay2a.html

• Purity :

  99.30

• Solubility :

  DMSO : 10 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles :

  O=C(C1=CC=C(C2=CN=C3C(NCC(C)C)=NC(C4=C5C=CC=NC5=CC=C4)=CN32)C=C1)NC6CC6

• Molecular Formula :

  C29H28N6O

• Molecular Weight :

  476.57

• References & Citations :

  [1]Jemaà M, et al. Characterization of novel MPS1 inhibitors with preclinical anticancer activity. Cell Death Differ. 2013 Nov;20 (11) :1532-45.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1382477-96-4]