Mps1-IN-4

• UNSPSC Description:

  Mps1-IN-4 is a selective Monopolar spindle 1 (Mps1) inhibitor with antiproliferative activity for cancer research[1].

• Target Antigen:

  Mps1

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mps1-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1CC1)C(C=C2)=CC=C2C3=CN=C4N3N=C(NC(C)(C)C(F)(F)F)C=C4NCC5CCOCC5

• Molecular Weight:

  516.56

• References & Citations:

  [1]Ken-Ichi Kusakabe, et al. Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity. J Med Chem. 2015 Feb 26;58(4):1760-75.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1263423-94-4