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Mps1-IN-4

CAT: 0804-HY-12658Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12658Size:1 Each
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Description
Mps1-IN-4 is a selective Monopolar spindle 1 (Mps1) inhibitor with antiproliferative activity for cancer research[1].
CAS Number
1263423-94-4
UNSPSC
12352005
Target
Mps1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mps1-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1CC1)C(C=C2)=CC=C2C3=CN=C4N3N=C(NC(C)(C)C(F)(F)F)C=C4NCC5CCOCC5
Molecular Formula
C26H31F3N6O2
Molecular Weight
516.56
References & Citations
[1]Ken-Ichi Kusakabe, et al. Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity. J Med Chem. 2015 Feb 26;58 (4) :1760-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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