Mps-BAY1

• UNSPSC Description:

  Mps-BAY1 is an MPS1 inhibitor with anticancer activity. Mps-BAY1 inhibits cell proliferation and induces apoptosis by activating mitotic catastrophe in cancer cells, generating global aneuploidy and polyploidy. Mps-BAY1 can be used in the study of colorectal cancer and cervical cancer[1].

• Target Antigen:

  Apoptosis; Mps1

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mps-bay1.html

• Smiles:

  N#CC1=C(NC2=NN3C=C(C4=CC=C(NC(CC5=CC=CC=C5)=O)C=C4)C=CC3=N2)C=CC=C1

• Molecular Weight:

  444.49

• References & Citations:

  [1]Jemaa, et al. "Characterization of novel MPS1 inhibitors with preclinical anticancer activity." Cell Death & Differentiation 20.11 (2013): 1532-1545.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1309593-24-5