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Mps-BAY1

CAT: 0804-HY-164501Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164501Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mps-BAY1 is an MPS1 inhibitor with anticancer activity. Mps-BAY1 inhibits cell proliferation and induces apoptosis by activating mitotic catastrophe in cancer cells, generating global aneuploidy and polyploidy. Mps-BAY1 can be used in the study of colorectal cancer and cervical cancer[1].
CAS Number
1309593-24-5
UNSPSC
12352005
Target
Apoptosis; Mitosis; Mps1
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mps-bay1.html
Smiles
N#CC1=C(NC2=NN3C=C(C4=CC=C(NC(CC5=CC=CC=C5)=O)C=C4)C=CC3=N2)C=CC=C1
Molecular Formula
C27H20N6O
Molecular Weight
444.49
References & Citations
[1]Jemaa, et al. "Characterization of novel MPS1 inhibitors with preclinical anticancer activity." Cell Death & Differentiation 20.11 (2013) : 1532-1545.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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