2-Hydroxy-3-methylanthraquinone

• UNSPSC Description:

  2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells[1].

• Target Antigen:

  Apoptosis; Src

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-hydroxy-3-methylanthraquinone.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(C=CC=C2)C(C3=CC(O)=C(C)C=C13)=O

• Molecular Weight:

  238.24

• References & Citations:

  [1]Shi Y, Wang CH, Gong XG. Apoptosis-inducing effects of two anthraquinones from Hedyotis diffusa WILLD. Biol Pharm Bull. 2008;31(6):1075-1078.

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Clinical Information:

  No Development Reported

• CAS Number:

  17241-40-6