Metformin-d6 (hydrochloride)

Metformin-d6 (hydrochloride)

• CAS Number: 1185166-01-1
• UNSPSC Description: Metformin-d6 (hydrochloride)e is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1].
• Target Antigen: AMPK; Autophagy; Mitophagy
• Type: Isotope-Labeled Compounds
• Related Pathways: Autophagy;Epigenetics;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Metabolic Disease; Cardiovascular Disease
• Purity: 98.79
• Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 50 mg/mL (ultrasonic)
• Smiles: NC(NC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=N)=N.[H]Cl
• Molecular Weight: 171.66
• References & Citations: [1]Soraya H, et al. Acute treatment with metformin improves cardiac function following NSC 37745 induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported