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Mazorelvimab

CAT: 0804-HY-P99727Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P99727Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mazorelvimab (CTB012) is an anti-rabies humanized IgG1κ monoclonal antibody that binds to the non-overlapping epitopes on the rabies virus (RABV) glycoprotein. Mazorelvimab binds to highly discontinuous conserved residues that are not in or near antigenic site III. Mezagitamab has potential application in the prevention of rabies[1][2].
CAS Number
2419087-89-9
Product Name Alternative
CTB012
UNSPSC
12352203
Target
RABV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mazorelvimab.html
Solubility
10 mM in DMSO
Smiles
[Mazorelvimab]
References & Citations
[1]Chao TY, et al. SYN023, a novel humanized monoclonal antibody cocktail, for post-exposure prophylaxis of rabies. PLoS Negl Trop Dis. 2017 Dec 20;11 (12) :e0006133. |[2]Chao TY, et al. In Vivo Efficacy of SYN023, an Anti-Rabies Monoclonal Antibody Cocktail, in Post-Exposure Prophylaxis Animal Models. Trop Med Infect Dis. 2020 Feb 21;5 (1) :31.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3

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