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Glabrene

CAT: 0804-HY-N3943Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3943Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC50 of 3.5 μM[1][2].
CAS Number
60008-03-9
UNSPSC
12352005
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/glabrene.html
Solubility
10 mM in DMSO
Smiles
OC1=C2C=CC(C)(C)OC2=C(C3=CC4=CC=C(O)C=C4OC3)C=C1
Molecular Formula
C20H18O4
Molecular Weight
322.35
References & Citations
[1]Somjen D, et al. Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues. J Steroid Biochem Mol Biol. 2004 Aug;91 (4-5) :241-6.|[2]Nerya O, et al. Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. J Agric Food Chem. 2003 Feb 26;51 (5) :1201-7
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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