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Glabrene

CAT: 0931-TN1690Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN1690Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
60008-03-9
Target
Estrogen/progestogen Receptor, Tyrosinase
Related Pathways
Proteases/Proteasome, Endocrinology/Hormones
Bioactivity
Glabrene, Liquiritin apioside, neolicuroside, and 18α2-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely the major contributors to the notable synergistic antioxidant activity when coupled with pea protein hydrolysates (PPHs) .Glabrene has estrogen-like activity, it can stimulate DNA synthesis in human endothelial cells (ECV-304; E304) and has a bi-phasic effect on proliferation of human vascular smooth muscle cells (VSMC) . Glabrene and isoliquiritigenin may serve as candidates for skin-lightening agents, they exert varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis.
Smiles
CC1(C)Oc2c(ccc(O)c2C=C1)C1=Cc2ccc(O)cc2OC1 |c:12,t:15|
Molecular Formula
C20H18O4
Molecular Weight
322.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Glabrene

Glabrene is an isoflavonoid.

CAS Number60008-03-9
PubChem CID480774
IUPAC Name8-(7-hydroxy-2H-chromen-3-yl)-2,2-dimethylchromen-5-ol
Molecular FormulaC20H18O4
Molecular Weight322.4
XLogP3.6
Topological Polar Surface Area58.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count24
Formal Charge0
Complexity538
SMILES
CC1(C=CC2=C(C=CC(=C2O1)C3=CC4=C(C=C(C=C4)O)OC3)O)C
InChI
InChI=1S/C20H18O4/c1-20(2)8-7-16-17(22)6-5-15(19(16)24-20)13-9-12-3-4-14(21)10-18(12)23-11-13/h3-10,21-22H,11H2,1-2H3
InChIKey
NGGYSPUAKQMTNP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Glabrene
CAS: 60008-03-9
CID: 480774
Formula: C20H18O4
MW: 322.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight322.4
XLogP33.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass322.12050905
Monoisotopic Mass322.12050905
Topological Polar Surface Area58.9 Ų
Heavy Atom Count24
Formal Charge0
Complexity538
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
TN1693-01Glabrone

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