Nampt activator-1
CAT:
804-HY-148815-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nampt activator-1
- CAS Number: 701929-65-9
- UNSPSC Description: Nampt activator-1 (compound 1) is a potent Nicotinamide phosphoribosyltransferase (NAMPT) activator, with EC50 of 3.3-3.7 μM[1].
- Target Antigen: NAMPT
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/nampt-activator-1.html
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(OCC)C1=CC=C(NC(NCC2=CC=NC=C2)=O)C=C1
- Molecular Weight: 299.32
- References & Citations: [1]Akiu M, et al. Discovery of 1-[2-(1-methyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-3-(pyridin-4-ylmethyl)urea as a potent NAMPT (nicotinamide phosphoribosyltransferase) activator with attenuated CYP inhibition.[J]. Bioorganic & medicinal chemistry letters, 2021, 43:128048.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported