Kallikrein 5-IN-2
CAT:
804-HY-148949-02
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Kallikrein 5-IN-2
- CAS Number: 2361160-57-6
- UNSPSC Description: Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].
- Target Antigen: Kallikrein
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/kallikrein-5-in-2.html
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: N=C(C1=CC=C(NCC2=NC=C(C3=CC=CC=C3)N2)C=C1OCC4=CC=CN=C4)N
- Molecular Weight: 398.46
- References & Citations: [1]Walker AL, et al. Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1454-1458.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported