Nampt activator-3
CAT:
804-HY-148948-04
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nampt activator-3
- CAS Number: 2790481-63-7
- UNSPSC Description: NAMPT activator-3, a NAT derivative, is a NAMPT activator with an EC50 of 2.6 μM and a KD of 132 nM. NAMPT activator-3 effectively protects cultured cells from FK866 (HY-50876)-mediated toxicity. NAMPT activator-3 exhibits strong neuroprotective efficacy in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model without any overt toxicity[1].
- Target Antigen: NAMPT
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/nampt-activator-3.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: N#CC1=CC=CC(C(C)(C)C)=C1OCC(NC2=CC=C(C=C2)O)=O
- Molecular Weight: 324.37
- References & Citations: [1]Leibo Wang, et al. Optimization of NAMPT activators to achieve in vivo neuroprotective efficacy. Eur J Med Chem. 2022 Jun 5;236:114260.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported