USP8-IN-3

USP8-IN-3

• CAS Number: 2477651-10-6
• UNSPSC Description: USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively[1].
• Target Antigen: Deubiquitinase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/usp8-in-3.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: [O-][N+](C1=CC=C(NC(NC2CCN(CC2)C3=CC=CC(C(F)(F)F)=N3)=S)C=C1)=O
• Molecular Weight: 425.43
• References & Citations: [1]Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported