PROTAC ERRα Degrader-1

PROTAC ERRα Degrader-1

• CAS Number: 2306388-84-9
• UNSPSC Description: PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an PROTAC estrogen-related receptor alpha (ERRa) degrader[1].
• Target Antigen: Estrogen Receptor/ERR; PROTACs
• Type: Reference compound
• Related Pathways: PROTAC;Vitamin D Related/Nuclear Receptor
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-erralpha-degrader-1.html
• Purity: 98.22
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(N1CC(N(CC(NCCNC(/C(C#N)=C/C2=CC(OC)=C(OCC3=C(C=C(C(F)(F)F)C=C3)C(F)(F)F)C=C2)=O)=O)CC1)=O)N4[C@@H](C5=CC=C(Cl)C=C5)[C@@H](C6=CC=C(Cl)C=C6)N=C4C7=C(C=C(OC)C=C7)OC(C)C
• Molecular Weight: 1108.91
• References & Citations: [1]Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, stored under nitrogen, away from moisture)
• Clinical Information: Phase 1