(rel)-PROTAC ERRα Degrader-1

• UNSPSC Description:

  (rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1. PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader[1].

• Target Antigen:

  Estrogen Receptor/ERR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/rel-protac-err-alpha-degrader-1.html

• Purity:

  98.18

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N(CCN1CC(NCCNC(/C(C#N)=C/C2=CC(OC)=C(OCC(C=CC(C(F)(F)F)=C3)=C3C(F)(F)F)C=C2)=O)=O)CC1=O)N4[C@@H](C5=CC=C(Cl)C=C5)[C@@H](C6=CC=C(Cl)C=C6)N=C4C(C=CC(OC)=C7)=C7OC(C)C

• Molecular Weight:

  1108.92

• References & Citations:

  [1]Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, stored under nitrogen, away from moisture)

• Clinical Information:

  No Development Reported