c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]

• UNSPSC Description:

  c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively[1].

• Target Antigen:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/c-arg-arg-arg-arg-nal-nal-nal.html

• Solubility:

  H2O

• Smiles:

  O=C(N[C@H](C(N[C@@H](C(N[C@@H](C1=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC2=CC(C=CC=C3)=C3C=C2)[C@@H](NC([C@@H](NC([C@H](NC([C@H](N1)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC4=CC(C=CC=C5)=C5C=C4)=O)CC6=CC(C=CC=C7)=C7C=C6

• Molecular Weight:

  1216.44

• References & Citations:

  [1]Sandeep Lohan, et al. Small Amphiphilic Peptides: Activity Against a Broad Range of Drug-Resistant Bacteria and Structural Insight into Membranolytic Properties. J Med Chem. 2022 Jan 13;65(1):665-687.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2619854-01-0