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Arg-Arg-AMC

CAT: 0804-HY-P4340Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P4340Size:1 Each
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Description
Arg-Arg-AMC is a highly selective substrate of Cathepsin B. Arg-Arg-AMC can be used to cathepsin B activity assay in cancer cells, while cathepsin B is assocaited with cell invasive and metastatic phenotype in numerous types of cancer[1].
CAS Number
263843-55-6
UNSPSC
12352209
Target
Cathepsin
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arg-arg-amc.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@@H](N)CCCNC(N)=N)=O)=O)C=C1O2)=CC2=O
Molecular Formula
C22H33N9O4
Molecular Weight
487.56
References & Citations
[1]Hulkower KI, et al. Fluorescent microplate assay for cancer cell-associated cathepsin B. Eur J Biochem. 2000 Jul;267 (13) :4165-70.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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