DSP-0565

• Description :

  DSP-0565 (compound 17a) is a strong, broad-spectrum anti-epileptic agent (AED) candidate with unique GABAergic function. DSP-0565 shows anti-convulsant activity in various models (scPTZ, MES, 6 Hz and amygdala kindling) with good safety margin[1].

• UNSPSC :

  12352005

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dsp-0565.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N)CC1=CC=CC=C1C2=CC=CC=C2F

• Molecular Formula :

  C14H12FNO

• Molecular Weight :

  229.25

• References & Citations :

  [1]Tanaka T, et al. Identification of 2- (2'-fluoro-[1,1'-biphenyl]-2-yl) acetamide as a Sodium Valproate-like broad spectrum anti-epileptic drug candidate. Bioorg Med Chem Lett. 2019 Jan 15;29 (2) :138-142.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [1226855-28-2]