DSP-0565

• UNSPSC Description:

  DSP-0565 (compound 17a) is a strong, broad-spectrum anti-epileptic agent (AED) candidate with unique GABAergic function. DSP-0565 shows anti-convulsant activity in various models (scPTZ, MES, 6 Hz and amygdala kindling) with good safety margin[1].

• Target Antigen:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dsp-0565.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N)CC1=CC=CC=C1C2=CC=CC=C2F

• Molecular Weight:

  229.25

• References & Citations:

  [1]Tanaka T, et al. Identification of 2-(2'-fluoro-[1,1'-biphenyl]-2-yl)acetamide as a Sodium Valproate-like broad spectrum anti-epileptic drug candidate. Bioorg Med Chem Lett. 2019 Jan 15;29(2):138-142.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 1

• CAS Number:

  1226855-28-2