2-MeS-ATP

• UNSPSC Description:

  2-MeS-ATP (2-Methylthio-ATP) is an analog of adenosine nucleotides and acts as a P2Y purinergic receptor agonist specific for adenosine nucleotide activation. 2-MeS-ATP is also able to inhibit the release of toxic mediators from macrophages stimulated by endotoxin (LPS). 2-MeS-ATP can be used in the study of endotoxin shock and inflammatory diseases[1].

• Target Antigen:

  P2Y Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Inflammation/Immunology; Others

• Assay Protocol:

  https://www.medchemexpress.com/2-mes-atp.html

• Smiles:

  O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(SC)N=C3N)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

• Molecular Weight:

  553.27

• References & Citations:

  [1]Proctor R A, et al. Protection of mice from endotoxic death by 2-methylthio-ATP[J]. Proceedings of the National Academy of Sciences, 1994, 91(13): 6017-6020.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  43170-89-4