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Seco Rapamycin ethyl ester

CAT: 0804-HY-133770-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-133770-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Seco Rapamycin ethyl ester is an open-ring metabolite of Rapamycin derivative. Seco-rapamycin is reported not to affect the mTOR function[1].
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/seco-rapamycin-ethyl-ester.html
Purity
85.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@H]1[C@@](C(C(N2[C@H](C(OCC)=O)CCCC2)=O)=O)(O)O[C@H](C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C([C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(/C=C/[C@H](C)C[C@@H]3CC[C@@H](O)[C@H](OC)C3)=O)=O)CC1
Molecular Formula
C53H83NO13
Molecular Weight
942.23
References & Citations
[1]Paine MF, et al. Identification of a novel route of extraction of sirolimus in human small intestine: roles ofmetabolism and secretion. J Pharmacol Exp Ther. 2002 Apr;301 (1) :174-86.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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