(S)-CPP (sodium)

• CAS Number:

  194979-70-9

• UNSPSC Description:

  (S)-CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/s-cpp-sodium.html

• Smiles:

  O=C(O[Na])[C@@H](Cl)CC1=CC=CC=C1

• Molecular Weight:

  206.60

• References & Citations:

  [1]Erne, D., et al.Helvetica Chimica Acta1980|[2]Paper-Based Electronic Tongue

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported