(S) -CPP (sodium)

• Description :

  (S) -CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S) -CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/s-cpp-sodium.html

• Smiles :

  O=C(O[Na])[C@@H](Cl)CC1=CC=CC=C1

• Molecular Formula :

  C9H8ClNaO2

• Molecular Weight :

  206.60

• References & Citations :

  [1]Erne, D., et al.Helvetica Chimica Acta1980|[2]Paper-Based Electronic Tongue

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [194979-70-9]