ZIP (TFA)

• Description:

  ZIP TFA is a selective peptide inhibitor of PKMζ. ZIP TFA injections can block the impairment in morphine conditioned place preference induced[1].

• UNSPSC:

  12352209

• Target:

  PKC

• Type:

  Peptides

• Related Pathways:

  Epigenetics; TGF-beta/Smad

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/zip-tfa.html

• Solubility:

  H2O

• Smiles:

  [{Myr-Ser}-IYRRGARRWRKL (TFA salt) ]

• Molecular Formula:

  C90H154N30O17.xC2HF3O2

• Molecular Weight:

  1928.38 (free acid)

• References & Citations:

  [1]Li Y, et, al. Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. J Neurosci. 2011 Apr 6;31 (14) :5436-46.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  Phase 4