Human CD4 Protein

Human CD4 Protein_x000D_ Catalog number: B2011878_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 20 µg_x000D_ Molecular Weight or Concentration: 250 µg/mL_x000D_ Supplied as: Solution_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20 °C_x000D_ Keywords: T-cell surface glycoprotein CD4 isoform 1 protein, CD4mut protein_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Jabbar MA. The human immunodeficiency virus type 1 Vpu protein: roles in virus release and CD4_downregulation Curr Top Microbiol Immunol. 1995;193:107-20._x000D_ 2: Adams WC, Berenson RJ, Karlsson Hedestam GB, Lieber A, Koup RA, Loré K. Attenuation of CD4+ T-cell function by human adenovirus type 35 is mediated by the knob protein J Gen Virol. 2012 Jun;93(Pt 6):1339-1344._x000D_ 3: Landi A, Timermans CG, Naessens E, Vanderstraeten H, Stove V, Verhasselt B. The human immunodeficiency virus (HIV) Rev-binding protein (HRB) is a co-factor for HIV-1 Nef-mediated CD4 downregulation J Gen Virol. 2016 Mar;97(3):778-785._x000D_ 4: Roncador G, Brown PJ, Maestre L, Hue S, Martínez-Torrecuadrada JL, Ling KL, Pratap S, Toms C, Fox BC, Cerundolo V, Powrie F, Banham AH. Analysis of FOXP3 protein expression in human_CD4+CD25+ regulatory T cells at the single-cell level Eur J Immunol. 2005 Jun;35(6):1681-91._x000D_ 5: Neri F, Giolo G, Potestà M, Petrini S, Doria M. CD4 downregulation by the human immunodeficiency virus type 1 Nef protein is dispensable for optimal output and functionality of viral particles in primary T cells J Gen Virol. 2011 Jan;92(Pt 1):141-50._x000D_ 6: Willey RL, Maldarelli F, Martin MA, Strebel K. Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of_CD4 J Virol. 1992 Dec;66(12):7193-200._x000D_ 7: Raja NU, Jabbar MA. The human immunodeficiency virus type 1 Vpu protein tethered to the CD4 extracellular domain is localized to the plasma membrane and is biologically active in the secretory pathway of mammalian cells: implications for the mechanisms of Vpu function Virology. 1996 Jun 1;220(1):141-51._x000D_ 8: Kawamura I, Koga Y, Oh-Hori N, Onodera K, Kimura G, Nomoto K. Depletion of the surface CD4 molecule by the envelope protein of human immunodeficiency virus expressed in a human_CD4+ monocytoid cell line J Virol. 1989 Sep;63(9):3748-54._x000D_ 9: Edwards TG, Hoffman TL, Baribaud F, Wyss S, LaBranche CC, Romano J, Adkinson J, Sharron M, Hoxie JA, Doms RW. Relationships between_CD4 independence, neutralization sensitivity, and exposure of a CD4_induced epitope in a human immunodeficiency virus type 1 envelope protein J Virol. 2001 Jun;75(11):5230-9._x000D_ 10: Tiganos E, Yao XJ, Friborg J, Daniel N, Cohen EA. Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule J Virol. 1997 Jun;71(6):4452-60. _x000D_ _x000D_ Products Related to Human CD4 Protein can be found at Proteins

Catalog Number: B2011878 (20 µg)

0.15

2

0.5