Products for Research Use Only
RegisterLogin

PCGF6, GST-tag Recombinant

CAT: 0421-55016Size: 50 µgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0421-55016Size:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Transcriptional repressor that modulates the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.
Description
Human Polycomb group RING finger protein 6 (PCGF6), GenBank Accession No. NM_001011663, a.a. 2-350 (end), with N-terminal GST-tag, MW=65.7 kDa, expressed in a baculovirus expression system.
UniProt
Q9BYE7
Tag
N-terminal GST-tag
Applications
Useful for protein binding assays, screening inhibitors, and selectivity profiling.
Purity
≥ 86%
Format
Aqueous buffer solution
Shipping Conditions
-80°C
Storage Conditions
≥ 6 months at -80°C
Calculated Molecular Weight
65.7 kDa
Formulation
40 mM Tris. pH 8.0,110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, and 20% glycerol.

UniProtKB · Q9BYE7

Polycomb group RING finger protein 6

PCGF6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BYE7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PCGF6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K3R4, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

Coiled coilZinc-finger

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Molecular function

Repressor

Biological process

TranscriptionTranscription regulation

Related Products

CatalogName
60038PDE4A10, GST-tag Recombinant
60010PDE1A, GST-tag Recombinant
55000L3MBTL1, GST-tag Recombinant
11708TNIK, GST-Tag Recombinant
101597-2TRAF6, GST-Tag Recombinant
60070PDE7A, GST-Tag Recombinant
60090PDE9A2, GST-tag Recombinant
60100PDE10A2, GST-Tag Recombinant
50007-2HDAC7, GST-tag Recombinant
60044PDE4C1, GST-tag Recombinant

Alternative Products

CatalogName
298443PCGF6, Recombinant, Human, aa2-350, GST-tag (Polycomb Group RING Finger Protein 6, Mel18 And Bmi1-Like RING Finger Protein, MBLR, RNF134)
RC-5397-01Recombinant Pcgf6 Antibody
ARM1997-01PCGF6 Recombinant Rabbit mAb
E30P10405Recombinant Human PCGF6 Protein
RP219611PCGF6 Recombinant Protein (Rat)
RP160667PCGF6 Recombinant Protein (Mouse)
bsm-33007R-01GST tag Recombinant Antibody
AN302031L-01Recombinant PCGF6 Monoclonal Antibody
RP022741PCGF6 Recombinant Protein (Human)
36194034PCGF6 Protein Lysate (Mouse) with C-HA Tag

Popular Products