CBX2, GST-tag Recombinant

CAT: 0421-55011Size: 100 µgDry Ice: YesHazardous: No

1 / 1

CAT#:0421-55011Size:100 µg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys119, rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.

Description

Human chromobox homolog 2 (CBX2), also known as SRXY5 and cell division cycle associated 6 (CDCA6), GenBank Accession No. NM_005189, a.a. 2-90, with N-terminal GST-tag, MW=37.3 kDa, expressed in anE. colicell expression system.

UniProt

Q14781

Tag

N-terminal GST-tag

Applications

Useful for protein binding assays, screening inhibitors, and selectivity profiling.

Purity

≥ 79%

Format

Aqueous buffer solution

Shipping Conditions

-80°C

Storage Conditions

≥ 6 months at -80°C

Calculated Molecular Weight

37.3 kDa

Formulation

40 mM Tris-HCl, pH 8.0,110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 20% glycerol.

UniProtKB · Q14781

Chromobox protein homolog 2

CBX2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q14781
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CBX2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q0VDA5, Q9BTB1

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorDNA-bindingRepressor

Cellular component

ChromosomeNucleus

Biological process

DifferentiationSexual differentiationTranscriptionTranscription regulation

Disease

Disease variant

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Related Products

Catalog	Name
55012	CBX2, His-tag Recombinant
55009	CBX1, GST-tag Recombinant
60039	PDE4A4B, GST-tag Recombinant
60099	PDE10A1, GST-tag Recombinant
60080	PDE8A1, GST-tag Recombinant
60046	PDE4D3, GST-tag Recombinant
101597-1	TRAF6, GST-Tag Recombinant
60031	PDE3B, GST-Tag Recombinant
60013	PDE1C, GST-Tag Recombinant
60110	PDE11A4, GST-tag Recombinant

Alternative Products

Catalog	Name
298386	CBX2, Recombinant, Human, aa2-90, GST-tag (Chromobox Homolog 2, SRXY5, Cell Division Cycle Associated 6, CDCA6)
298387	CBX2, Recombinant, Human, aa2-90, His-Tag (Chromobox Homolog 2, SRXY5, Cell Division Cycle Associated 6, CDCA6)
MBS7610482-01	Recombinant Human CBX2
bsm-62125R-TR	CBX2 Recombinant Antibody
RC-16073-01	Recombinant CBX2 Antibody
bsm-33007R-TR	GST tag Recombinant Antibody
TP725902	CBX2 Human Recombinant Protein
CSB-RA632623A0HU-01	CBX2 Recombinant Monoclonal Antibody
RP005752	CBX2 Recombinant Protein (Human)
RP193319	CBX2 Recombinant Protein (Rat)