Cathepsin L-IN-2
CAT:
804-HY-115733-03
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Cathepsin L-IN-2
- CAS Number: 108005-94-3
- UNSPSC Description: Cathepsin L-IN-2 (Z-Phe-Phe-FMK) is a potent and irreversible cathepsin L and cathepsin B inhibitor[1][2].
- Target Antigen: Cathepsin
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/cathepsin-l-in-2.html
- Purity: 98.27
- Solubility: DMSO : 42.5 mg/mL (ultrasonic)
- Smiles: O=C(OCC1=CC=CC=C1)NC(CC2=CC=CC=C2)C(NC(CC3=CC=CC=C3)C(CF)=O)=O
- Molecular Weight: 462.51
- References & Citations: [1]Jonathan Frew, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020 Mar 16;15(1):21.|[2]Kirsi Ravanko, et al. Cysteine cathepsins are central contributors of invasion by cultured adenosylmethionine decarboxylase-transformed rodent fibroblasts. Cancer Res. 2004 Dec 15;64(24):8831-8.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported