Cathepsin D and E FRET Substrate (acetate)

Cathepsin D and E FRET Substrate (acetate)

• UNSPSC Description: Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D[1].
• Target Antigen: Cathepsin
• Type: Peptides
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cathepsin-d-and-e-fret-substrate-acetate.html
• Purity: 99.12
• Solubility: H2O : 10 mg/mL (ultrasonic)
• Smiles: O=C(N1[C@@H](CCC1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCNC2=C(C=C(C=C2)[N+]([O-])=O)[N+]([O-])=O)C(N[C@@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O)[C@H](CCCCN)NC(CNC(CC(C5=CC=C(OC)C=C5O6)=CC6=O)=O)=O.CC(O)=O
• Molecular Weight: 1816.15
• References & Citations: [1]Y Yasuda, et al. Characterization of new fluorogenic substrates for the rapid and sensitive assay of cathepsin E and cathepsin D. J Biochem
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported