17β-HSD10-IN-1

17β-HSD10-IN-1

• CAS Number: 2316765-78-1
• UNSPSC Description: 17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/17β-hsd10-in-1.html
• Solubility: DMSO : 25 mg/mL (ultrasonic)
• Smiles: O=C(NC1=CC=C(C(Cl)=C1)O)NC(SC2=C3)=NC2=CC=C3NC(C)=O
• Molecular Weight: 376.82
• References & Citations: [1]Benek O, et al. Development of submicromolar 17尾-HSD10 inhibitors and their in vitro and in vivo evaluation. Eur J Med Chem. 2023 Oct 5;258:115593.聽
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported